Annual and transition report of foreign private issuers [Sections 13 or 15(d)]

Revenues (Details)

v3.26.1
Revenues (Details)
€ in Thousands, $ in Thousands, $ in Thousands
1 Months Ended 12 Months Ended
Oct. 31, 2025
USD ($)
Jun. 28, 2021
Mar. 16, 2021
USD ($)
Jul. 31, 2019
USD ($)
Mar. 31, 2015
USD ($)
Mar. 31, 2015
CAD ($)
Dec. 31, 2025
USD ($)
Dec. 31, 2025
EUR (€)
Sep. 24, 2024
USD ($)
Apr. 06, 2018
USD ($)
Revenues [Line Items]                    
Additional payment           $ 2,000        
Net sales percentage         16.50% 16.50%        
Transfer price rate 10.00%                  
Terms of agreement       $ 750            
Additional achieved milestone     $ 40,450 3,250            
Revenues recognized             $ 2,000      
Non-refundable payment     $ 2,250         € 250    
Milestone payment percentage             30.00% 30.00%    
Finite-lived patents, gross                 $ 250  
Maximum [Member]                    
Revenues [Line Items]                    
Percentage of royalties on net sales   40.00%                
Minimum [Member]                    
Revenues [Line Items]                    
Percentage of royalties on net sales   15.00%                
Cipher Pharmaceuticals [Member]                    
Revenues [Line Items]                    
Upfront payment         $ 1,292 $ 1,650        
Chong Kun Dang Pharmaceuticals Corp. [Member]                    
Revenues [Line Items]                    
Terms of agreement             $ 1,500      
Additional achieved milestone             500      
Gebro Holding GmbH [Member]                    
Revenues [Line Items]                    
Terms of agreement             1,850 € 1,500    
Additional achieved milestone             $ 720 € 600    
Description of additional payments             Under the Distribution and Supply Agreement, the Company is entitled to € 1,500 thousands upon execution of the agreement. In addition, the Company is also entitled to milestone payments upon achieving certain clinical, launch and sales milestones, as follows: (i) € 300 thousand upon initiation of the ACRobat Phase III clinical trial for the treatment of rheumatoid arthritis and € 300 thousand upon the initiation of the COMFORT Phase III clinical trial for the treatment of psoriasis, (ii) between € 750 thousand and € 1,600 thousand following first delivery of commercial launch quantities of Piclidenson for either the treatment of rheumatoid arthritis or psoriasis, and (iii) between € 300 thousand and up to €4,025 thousand upon meeting certain net sales. In addition, following regulatory approval, the Company shall be entitled to future royalties on net sales of Piclidenoson in the territories and payment for the manufacturing Piclidenoson. Under the Distribution and Supply Agreement, the Company is entitled to € 1,500 thousands upon execution of the agreement. In addition, the Company is also entitled to milestone payments upon achieving certain clinical, launch and sales milestones, as follows: (i) € 300 thousand upon initiation of the ACRobat Phase III clinical trial for the treatment of rheumatoid arthritis and € 300 thousand upon the initiation of the COMFORT Phase III clinical trial for the treatment of psoriasis, (ii) between € 750 thousand and € 1,600 thousand following first delivery of commercial launch quantities of Piclidenson for either the treatment of rheumatoid arthritis or psoriasis, and (iii) between € 300 thousand and up to €4,025 thousand upon meeting certain net sales. In addition, following regulatory approval, the Company shall be entitled to future royalties on net sales of Piclidenoson in the territories and payment for the manufacturing Piclidenoson.    
Vetbiolix [Member]                    
Revenues [Line Items]                    
Description of additional payments             On August 6, 2018, the Company entered into a License, Collaboration and Distribution Agreement with CMS Medical Venture Investment Limited (“CMS Medical”) for the commercialization of Piclidenoson for the treatment of rheumatoid arthritis, psoriasis and Namodenoson for the treatment of advanced liver cancer and NAFLD/NASH in China (including Hong Kong, Macao and Taiwan). On August 6, 2018, the Company entered into a License, Collaboration and Distribution Agreement with CMS Medical Venture Investment Limited (“CMS Medical”) for the commercialization of Piclidenoson for the treatment of rheumatoid arthritis, psoriasis and Namodenoson for the treatment of advanced liver cancer and NAFLD/NASH in China (including Hong Kong, Macao and Taiwan).    
Revenues recognized                 $ 271  
CMS Medical Venture Investment Limited [Member]                    
Revenues [Line Items]                    
Upfront and milestone payments payable                   $ 2,000
Regulatory Milestones [Member]                    
Revenues [Line Items]                    
Additional achieved milestone             $ 14,000      
Sales Milestones [Member]                    
Revenues [Line Items]                    
Additional achieved milestone             58,500      
Kyongbo Pharm Co Ltd [Member]                    
Revenues [Line Items]                    
Revenues recognized       $ 750            
Ewopharma [Member]                    
Revenues [Line Items]                    
Terms of agreement             $ 2,250      
Percentage of royalties on net sales     17.50%              
South Korea [Member]                    
Revenues [Line Items]                    
Net sales percentage 23.00%                  
Liver Cancer Indication [Member]                    
Revenues [Line Items]                    
Upfront and milestone payments payable $ 3,000                  
NASH [Member]                    
Revenues [Line Items]                    
Upfront and milestone payments payable $ 6,000