Annual and transition report of foreign private issuers [Sections 13 or 15(d)]

Revenues (Details)

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Revenues (Details)
€ in Thousands, $ in Thousands, $ in Thousands
1 Months Ended 12 Months Ended
Mar. 16, 2021
USD ($)
Jul. 31, 2019
USD ($)
Mar. 31, 2015
CAD ($)
Mar. 31, 2015
USD ($)
Mar. 31, 2015
CAD ($)
Dec. 31, 2024
USD ($)
Dec. 31, 2023
USD ($)
Dec. 31, 2023
EUR (€)
Dec. 31, 2024
EUR (€)
Revenues [Line Items]                  
Royalty payments (in Dollars)     $ 2,000            
Percentage of remaining net sales     16.50% 16.50% 16.50%        
Transfer price rate           10.00%      
Terms of agreement | €               € 1,500  
Additional achieved milestone $ 40,450 $ 3,250              
Revenues recognized   750       $ 2,000      
Non-refundable payment $ 2,250         $ 250      
Milestone payment percentage           30.00%      
Patents (in Euro) | €                 € 250
Liver Cancer Indication [Member]                  
Revenues [Line Items]                  
Upfront and milestone payments payable           $ 3,000      
NASH [Member]                  
Revenues [Line Items]                  
Upfront and milestone payments payable           6,000      
Regulatory Milestones [Member]                  
Revenues [Line Items]                  
Additional achieved milestone           14,000      
Sales Milestones [Member]                  
Revenues [Line Items]                  
Additional achieved milestone           $ 58,500      
Royalty [Member]                  
Revenues [Line Items]                  
Percentage of remaining net sales 17.50%         15.00%     15.00%
Revenue Benchmark [Member]                  
Revenues [Line Items]                  
Percentage of remaining net sales           40.00%     40.00%
Cipher Pharmaceuticals [Member]                  
Revenues [Line Items]                  
Upfront payment       $ 1,292 $ 1,650        
Chong Kun Dang Pharmaceuticals Corp [Member]                  
Revenues [Line Items]                  
Terms of agreement           $ 1,500      
Additional achieved milestone           $ 500      
Gebro Holding GmBH [Member]                  
Revenues [Line Items]                  
Terms of agreement             $ 1,850    
Additional achieved milestone             $ 720 € 600  
Description of additional payments           Under the Distribution and Supply Agreement, the Company is entitled to € 1,500 thousands upon execution of the agreement. In addition, the Company is also entitled to milestone payments upon achieving certain clinical, launch and sales milestones, as follows: (i) € 300 thousand upon initiation of the ACRobat Phase III clinical trial for the treatment of rheumatoid arthritis and € 300 thousand upon the initiation of the COMFORT Phase III clinical trial for the treatment of psoriasis, (ii) between € 750 thousand and € 1,600 thousand following first delivery of commercial launch quantities of Piclidenson for either the treatment of rheumatoid arthritis or psoriasis, and (iii) between € 300 thousand and up to €4,025 thousand upon meeting certain net sales. In addition, following regulatory approval, the Company shall be entitled to future royalties on net sales of Piclidenoson in the territories and payment for the manufacturing Piclidenoson.      
Vetbiolix [Member]                  
Revenues [Line Items]                  
Description of additional payments           On August 6, 2018, the Company entered into a License, Collaboration and Distribution Agreement with CMS Medical Venture Investment Limited (“CMS Medical”) for the commercialization of Piclidenoson for the treatment of rheumatoid arthritis, psoriasis and Namodenoson for the treatment of advanced liver cancer and NAFLD/NASH in China (including Hong Kong, Macao and Taiwan).      
Revenues recognized           $ 271      
CMS Medical Venture Investment Limited [Member]                  
Revenues [Line Items]                  
Upfront and milestone payments payable           2,000      
Kyongbo Pharm Co.[Member]                  
Revenues [Line Items]                  
Terms of agreement   $ 750              
Ewopharma [Member]                  
Revenues [Line Items]                  
Terms of agreement           $ 2,250      
South Korea [Member]                  
Revenues [Line Items]                  
Percentage of remaining net sales           23.00%     23.00%